Nursing Pharmacology Chapter 5:  Autonomic Pharmacology: Cholinergic Drugs

 

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Spectrum of Action of Choline Esters

Choline Ester

Sensitivity to ACHE

Cardiovascular

Gastrointestinal

Urinary Bladder

Eye (Topical)

Atropine Sensitive

Activity at Nicotinic Sites

Acetylcholine

Methacholine

Carbachol

No

Bethanechol

No

??

No

  1. Modified from Table 7-1: Brown, J.H. and Taylor, P. Muscarinic Receptor Agonists and Antagonists, In, Goodman and Gillman's The Pharmacological Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) The McGraw-Hill Companies, Inc.,1996, p 143

  2. Brown, J.H. and Taylor, P. Muscarinic Receptor Agonists and Antagonists, In, Goodman and Gillman's The Pharmacological Basis of Therapeutics,c(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, p 142-143.

 
 
 
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